I use Twitter lists to make it easier to sort through high volumes of tweet for information about specific topics. For instance, if I want to find out what people in music education are talking about, I click on my list titled "music education" and it only shows me music educators I have added to that list rather than all of the Twitter users I follow.
TweeDeck allows you to have multiple twitter accounts, lists, profiles, etc. displayed all at once. I use this tool on my laptop when I want to quickly browse my various Twitter lists.